The Clinical Skills Centre serves as the main procedural skills teaching facility for students of the Northern Clinical School (University of Sydney) and junior medical staff of the adjoining Royal North Shore Hospital. The Centre also partners with a number of professional teaching bodies and medical technology suppliers to provide postgraduate training, research, new technology showcases, and professional development opportunities for training surgeons.

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The Clinical Skills Centre is staffed by a team of Clinical Skills Educators and a Senior Technical Officer (University of Sydney).